BDBM50590061 CHEMBL5196432

SMILES [H][C@]12CN(CC(F)(F)F)CCN1c1cc3c(N[C@H](C)c4cccc(C(F)F)c4F)nc(C)nc3cc1OCC2

InChI Key InChIKey=LLWSSGBFYYSLTH-ZBFHGGJFSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50590061   

TargetSon of sevenless homolog 1(Homo sapiens (Human))
Wuhan University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50590061(CHEMBL5196432)
Affinity DataIC50:  16nMAssay Description:Inhibition of SOS1 in human DLD-1 cells assessed as reduction in ERK phosphorylation incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed